This was a large international trial  run in the Emergency Department. It was looking at the use of Tranexamic acid for the treatment of significant traumatic brain injury. Tranexamic acid has been used to stop bleeding in elective surgery for many years, and the CRASH 2 Trial highlighted the benefit of this drug in patients who had suffered a trauma and were having a catastrophic bleed. This study wanted to know if giving Tranexamic acid in traumatic brain injuries improves mortality rate.